Carcinoma of the Lower Uterine Segment: A Newly Described Association With Lynch Syndrome
نویسندگان
چکیده
منابع مشابه
Carcinoma of the Lower Uterine Segment (LUS): Clinicopathological Characteristics and Association with Lynch Syndrome
Endometrial cancer arises from the uterine body and fundus in many cases, but can also originate from the lower region of the uterine body through the upper region of the cervix. Such tumors are referred to as carcinoma of the lower uterine segment (LUS) or isthmus, and account for 3-6.3% of all cases of endometrial cancer. This relatively low incidence has permitted performance of only small-s...
متن کاملRelationship of lower uterine segment cancer with Lynch syndrome: A novel case with an hMLH1 germline mutation
Lynch syndrome is a genetic disease that often develops in patients with endometrial cancer and is caused by abnormal DNA mismatch repair (MMR) genes. In the United States, it was recently reported that the prevalence of Lynch syndrome with an hMSH2 mutation in patients with endometrial cancer in the lower uterine segment (LUS) is much greater tha...
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We read with interest the study published by Ferrer et al. about a patient with Lynch syndrome (LS) who presented a colorectal carcinoma (CRC) and a synchronous clear cell renal carcinoma (CCRC) (1). From our point of view, it would be interesting to emphasize some aspects of this patient, such as the type of mutation carried by the patient, and its cancer familial tree. In addition, we would l...
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A 40-year-old Caucasian male presented to the Emergency Department complaining of intermittent painless frank haematuria. Past medical history was significant for Hereditary Non-Polyposis Colon Cancer (HNPCC) and a prophylactic total colectomy. Computed tomography urogram showed thickening in the posterior wall of the bladder. Cystoscopy showed a small bladder mass. Histology showed a papillary...
متن کاملClear cell carcinoma of the lower uterine segment: A case report
Uterine carcinoma of the lower uterine segment (LUS) is a rare tumor that accounts for 3-3.5% of cases of uterine malignant cancer. The tumor arises from the lower region of the uterine body through the upper region of the cervix. The present study reported a case of clear cell carcinoma that originated from the LUS. A 50-year-old woman visited a local hospital due to irregular vaginal bleeding...
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ژورنال
عنوان ژورنال: Journal of Clinical Oncology
سال: 2008
ISSN: 0732-183X,1527-7755
DOI: 10.1200/jco.2008.18.6296